SEQAfrica - Phase 1

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Whole Genome Sequencing (WGS) capacity in Africa.

This Phase 1 grant delivering technical assistance and supporting Whole Genome Sequencing (WGS) capacity in Africa.

This grant focused on establishing a regional centre for sequencing to allow the investigation of outbreaks, unusual resistance phenotypes, or delineation of the flow of organisms/genes across human/animal/agricultural and aquaculture sectors. This grant sought to reduce in-country costs for accessing sequencing, however, in-country expertise was still be required for appropriate sampling, identification of organisms for sequencing, sample storage, DNA extraction and downstream analysis.

Lead Grantee:

National Food Institute, Technical University of Denmark

Sub-Grantees:

Kilimanjaro Clinical Research Institute; National Institute for Communicable Diseases South Africa; University of Ibadan

Duration:

May 2019 - Sep 2023

Value:

£6,633,221.97

Countires:

Eswatini, Kenya, Malawi, Tanzania, Uganda, Zambia, Zimbabwe, Burkina Faso, Ghana, Nigeria, Senegal, Sierra Leone

Objectives

• Regional sequencing centres for East and Southern Africa, and West Africa, are developed to support whole genome sequencing for AMR surveillance in Fleming Fund countries
• Regional training is established and rolled-out in Fleming Fund countries
• Whole genome sequencing data is used to enhance AMR surveillance across One Health sectors