World Health Organization

---

A global cross-sectoral approach is required to address the threat of antimicrobial resistance (AMR).

The Food and Agriculture Organization of the United Nations (FAO), the World Organisation for Animal Health (WOAH), the World Health Organization (WHO) and the United Nations Environment Programme (UNEP) work collaboratively as a Quadripartite with the aim of tackling AMR through a One Health approach. They support countries to develop and implement National Action Plans (NAPs) on AMR.

Since 2016 the Fleming Fund has provided funding to the WHO to tackle AMR as part of a joint proposal for funding from the then Tripartite. Funding has been used to: support countries to develop and implement NAPs, develop global guidance and protocols on AMR and antimicrobial Consumption (AMC), support the establishment of effective AMR governance systems, increase the technical capacity of countries, raise awareness of AMR and change behaviours in targeted sectors, and support effective collaboration across the Quadripartite.

This work creates the enabling environment for the generation, sharing, and use of AMR surveillance data and directly supports the implementation of the Fleming Fund country grants programme.

Partners:

World Health Organization (WHO)

Timeline:

Phase 1: August 2016 - August 2022

Phase 2: Until March 2025

Phase 2.5: April 2025 – March 2026

Value:

£9.9m

Priority countries:

Countries across the WHO AFRO, WPRO, SEARO and EMRO regions.

Objectives

• To support countries to accelerate and sustain implementation and monitoring of evidence-based national action plans on antimicrobial resistance.
• To optimise the use of antimicrobials and diagnostics in human health
• To enhance the generation and use of data for policy, legislation and programme activities.

Achievements and Milestones

• Increased number of countries submitting AMR surveillance data to GLASS, including Fleming Fund supported countries.
• Operational tools developed for generic protocol for national AMR surveys of prevalence, health and economic burden, providing countries with a template for specific protocols.
• Publication of Gender and AMR guidance to address inequalities with a people centred approach, providing policy- makers with evidenced-based recommendations when developing National Action Plans (NAP).
• New online platform for TrACSS deployed on behalf of the Quadripartite with a 96% response rate from countries in 2024. The new platform has improved functionalities, with the ability to compare countries and regions.
• AMR workforce technical capacity supported across the regions including Fleming Fund supported countries, with over 3,000 participants trained.
• More than 11,000 enrolled in e-learning courses developed through the Fleming Fund grant.